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Enhancing antioxidant defenses through dietary intake, pharmacological agents, or upregulation of endogenous antioxidant systems offers a promising strategy to protect the BBB and combat the deleterious effects of oxidative stress in the CNS [27,38,143]

Intestinal permeability refers to movement of molecules via the transcellular endocytosis or paracellular pathways

Julius D, Blair L, Brake A, Sprague G, Thorner J (1983) Yeast alpha factor is processed from a larger precursor polypeptide: the essential role of a membrane-bound dipeptidyl aminopeptidase

Ann Neurol 31: 286292

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